Interdisciplinary Electives

SOMI 220. Core Topics in Biomedical Sciences

Prerequisite: acceptance to School of Medicine or second-year student in School of Pharmacy and Pharmaceutical Science (SPPS)

This course prepares students for the first-year medical school curriculum at UCSD, focusing on the complex areas of immunology, physiology, molecular biology and genetics, as well as study and time-management skills needed for the rapid medical school academic pace.

Laiken

Summer quarter

Prerequisite: open only to first-year medical students concurrently taking SOMI 204

Laboratory experiences in basic biochemical techniques provide the following:
(1) molecular weight determinations, kinetic analyses, isozyme identification, and enzyme purification of lactate ehydrogenase.
(2) a membrane transport experiment with 14C, and
(3) a project involving the polymerase chain reaction (PCR)

Van der Geer

Fall quarter

Prerequisite: SOMI 211

Advanced cardiac life support provides training in the physiology, pharmacology, and practical skills necessary to direct the resuscitation of the victim of cardiac arrest. Successful completion yields certification as a provider in ACLS by the American Heart Association.

Shumaik

Fall, winter, and spring quarters

PALS is a two-day course in pediatric resuscitation. It is the pediatric equivalent of ACLS, approved by the American Heart Association. The course covers epidemiology, physiology, assessment, and treatment of pediatric cardiopulmonary arrests. It also covers pediatric cardiac dysrhythmias and newborn resuscitation.

Harley

Fall, winter, and spring quarters

Prerequisite: consent of instructor

Lectures and practical sessions expose students to the varied clinical settings of emergency medicine, including observational time in the emergency department at the 911 dispatch center, and on a paramedic ride-along. Discussions will include introductions to pediatric emergency medicine, prehospital care, air medical transport, resuscitation, toxicology, hyperbaric medicine, and disaster medicine. A suture lab is also held.

Schneir

Fall and winter quarters

Prerequisite: none

History of scientific misconduct, current issues in misconduct, authorship, conflict of interest, plagiarism, fabrication, falsification, data management, experimental design, and whistleblowing.

Kalichman

Spring quarter

Prerequisite: MSTP student in graduate program

This elective course is designed for MSTP students currently enrolled in their graduate programs. The goal of the course is to provide students with the opportunity to learn in clinical settings to enhance their clinical skills throughout their graduate school education. Students may select a clinical venue and a UCSD faculty member with whom they wish to work. Students will learn by observing and participating in the care of patients, as appropriate and according to their skill level under the direct supervision of a UCSD faculty member. The course will help to prepare students for re-entry into their School of Medicine third-year core clerkships, upon completion of their graduate programs.

Insel

Fall, Winter, Spring quarter

Prerequisite: second year medical student

Second year students examine clinical, psychosocial and spiritual issues of patients, their families, and themselves. Each student follows a patient and family cared for by San Diego Hospice to better understand the clinical issues. Interdisciplinary faculty guide seminar discussions on the role of the physician, symptom control, grief and bereavement, ethical decision-making, and family systems theory.

Lewis, Savoia

Winter quarter

Prerequisite: Fourth year medical student

The student develops and conducts a research project in palliative medicine. Clinical studies are developed and condcuted under supervision of appropriate faculty. Research involving human subjects must have San Diego Hospice IRB approval prior to implementation.

von Gunten, Savoia

All quarters

Prerequisite: none

This course will cover "ethical" issues in academia, including dishonesty, plagiarism, attribution, sexual misconduct, correcting errors, political activity, dealing with collaborators, etc. We will also discuss "survival" issues, including job hunting, grant preparation, journal reviews, writing letters of recommendation, mentoring, etc.

Kalichman, Elman

Winter quarter

Prerequisite: first-year medical student

A practical course covering diagnosis and treatment of injuries and illnesses encountered in the wilderness environment including cold, heat, high altitude, diving medicine, outdoor orthopedic trauma, plant and marine life poisonings, and survival in the wilderness. Includes 2 optional weekend workshops.

Van Hoesen

Winter quarter

Prerequisite: none

This course will develop and apply the theory of clinical trials design and analysis, discuss the practical issues of financing and implementing clinical trials, and describe issues of monitoring trials and working in cooperative groups. The scholar will design and present to a group of peers a concept sheet for a phase I/II and phase II/II clinical trial.

McCutchen

Winter quarter

Prerequisite: none

Scholars will recognize and understand different types of study designs, the relative strengths and limitations of each, and the proper choice of study design in conducting their own research. They will also be able to identify and calculate the correct measure of risk for each study design. Participants will recognize major sources of bias, confounding and misclassification, and understand design and analysis methods of dealing with each. They will also be familiar with criteria to differentiate association from causation.

Wingard

Spring quarter

Prerequisite: none

Scholars will evaluate relevant outcomes in patient-oriented research from the patient (quality-of-life) and societal (economic) perspectives and locate potential resources for assessing the relevant outcomes in a wide variety of study designs. They will also be able to describe the relative strengths of different health services research approaches to a clinical problem. Finally, they will understand the components of clinical practice guidelines, including patient preferences, and how these guidelines both depend upon as well as inform patient-oriented research.

Ganiats

Summer quarter

Prerequisite: none

Scholars will understand principles of measurement of clinical data, recognize data types, and correctly identify statistical methods appropriate for analysis of a given clinical data set. They will gain experience in assembling a clinical dataset in formats suitable for analysis by STATA or other comparable statistical packages. They will learn skills to conduct graphical and numerical exploratory data analysis, comparative tests of categorical, ordinal, and continuous data, linear and logistic regression analysis, and survival analysis by life table and Kaplan-Meier techniques.

Mathews

Fall quarter

Prerequisite: Biostatistics I (CLRE 254/SOMI 283)

Scholars will understand and conduct biostatistical analyses including: multiple linear and logistic regression, survival analysis, and Cox and extended Cox regression. The scholar will also be familiar with person-time rate analysis with Poisson regression and longitudinal data analysis in the presence of missing values and varying measurement times.

Mathews

Winter quarter

Prerequisite: none

This course provides an orienation to database design and management and covers key issues regarding data handling for clinical research and clinical trials. Scholars will also become familiar with technology assessment and decision-making methods and analysis.

Masys

Spring quarter

Prerequisite: CLRE 250/SOMI 280. Patient-Oriented Research I

This course will review the ethics and basic regulatory issues for research involving human subjects; the principles of data management for clinical research, including architecture, access and confidentiality, and integrity of databases; and skills in graphic and verbal presentation of research data. Scholars will prepare a mock submission to an IRB for peer review and practice presenting graphic and tabular data.

McCutchen

Summer quarter

Prerequisite: CLRE 251/SOMI 281. Epidemiology I

Scholars will select the appropriate sampling methods and determine the sample size necessary for specific projects and adjust for confounding. Participants will be familiar with several specialized analytic techniques, including matched, cluster, and meta-analyses. They will also be familiar with methodological issues unique to ecological, behavioral, and genetic studies.

Wingard

Fall quarter

Prerequisite: Clinical Research MAS Program or permission of department

Students participate in two series of weekend seminars on professional development topics that will focus on skills and knowledge to enhance the ability of clinical researchers to be successful. Seminar topics may include grant writing, scientific written communication skills, research management, team building and collaboration, leadership skills, career development in the clinical research field, negotiation skills, public presentation skills, research project management, and research budgeting/financial management.

Boss

Spring quarter

Prerequisites that may be concurrent: CLRE 250/SOMI280, CLRE 251/SOMI281, CLRE 252/SOMI282, CLRE 253/SOMI283, CLRE 254/SOMI284, CLRE 255/SOMI285, CLRE 256/SOMI286, and CLRE 257/SOMI287.

The ISP is the cornerstone of the MAS program. Students will be involved in a high-level clinical research project that integrates what they have learned in their formal coursework. The ISP will be an independent and creative scholarly activity in an area related to one or more of the topics covered in the formal curriculum. Students' work will be evaluated by a committee of faculty, and may also include industry advisors when appropriate.

Mehta

All quarters

Prerequisite: fourth-year medical student

This course provides instruction in the outpatient management of acute disease as encountered in the emergency room. The student will have direct patient care responsibility under the direction of full-time Emergency Medicine faculty. Technical and procedural skills are emphasized.

Schneir

All quarters

Prerequisite: fourth-year medical student

This course provides instruction in the outpatient management of acute disease as encountered in the emergency room. The student will have direct patient care responsibility under the direction of full-time Emergency Medicine faculty. Technical and procedural skills are emphasized.

Schneir

All quarters

Prerequisite: fourth-year medical student

This course provides instruction in the outpatient management of acute disease as encountered in the emergency room. The student will have direct patient care responsibility under the direction of full-time Emergency Medicine faculty. Technical and procedural skills are emphasized.

Schneir

All quarters

Prerequisite: fourth-year medical student

The Medical Toxicology Service provides inpatient and outpatient consultations at three (3) area hospitals, UCSDMC/Hillcrest, UCSD/ Thornton, and Mercy. In addition, an admitting service is available at both UCSD Hospitals. This elective entails participation with on-call responsibilities which consist of sharing call with attendings, fellows, or residents rotating on service. Daily rounds are led by the Fellow or Attending with an emphasis on bedside teaching. Students participate in the weekly Toxicology Journal Club, and students are expected to give at least one formal presentation on a toxicology-related topic. Student will be involved in the activities of the Regional Poison Center when not involved in a consultation.

Williams, Clark

All quarters

Prerequisite: fourth year medical student

The student participates as a physician member of the interdisciplinary hospice team caring for patients and families with advanced illness in the inpatient and home programs of the San Diego Hospice. The student will have direct patient care responsibility supervised by full-time board certified palliative medicine faculty.

Herbst, Savoia

All quarters

Anesthesiology

ANES 223. Introduction to the Politics of Medicine

Prerequisite: medical student

Current legislative issues pertaining to medicine will be discussed. Students will learn how they can remain informed about these issues and how they can become personally involved in shaping public policy on health care. Speakers will include incumbent state legislators as well as recognized experts in the areas of health care financing, residency training conditions and medical malpractice.

Hertzka

Fall quarter

Prerequisite: consent of instructor

This weekly participatory lecture/seminar will present an overview of the decision making process. The goal is to enhance the student's ability to make sound professional and personal decisions. Course material, drawn from medicine, psychology, business, and politics, will be clinically or personally relevant. Teamwork is emphasized. Extensive group exercises, discussions, debates, and role plays are employed.

Weinger

Winter quarter

Prerequisite: medical student

This is a hands-on interactive course. The student will have both patient and faculty interaction and learn how to perform a pain history and physical, develop a differential diagnosis and treatment plan and have daily pain mechanisms/management didactics.

Wallace

Fall, winter, spring quarters

Prerequisite: Consent of Instructor

This course presents the physiology, pathology, and molecular biology of the peripheral nervous system with emphasis on mechanisms of nerve degeneration, regeneration and pain. Indications and techniques for diagnostic and therapeutic intervention by anesthesiologists will also be covered.

Myers, Campana

Fall quarter

Prerequisite: Second year medical student

A clinical elective with emphasis on respiratory and cardiac physiology as illustrated on patients. Students will have hands-on operating room experience with normal and abnormal physiologic events, pharmacologic therapy.

Greenberg

Fall, winter, and spring quarters

Prerequisite: consent of instructor

Independent study.

Staff

All quarters

Prerequisite: approved ISP proposal

Independent Study Project (ISP).

Staff

All quarters

Prerequisite: fourth-year medical student

During this 4 week elective, a student participates in all activities of the Anesthesia Services. A tutor is assigned to each student. Throughout the four weeks, this team provides anesthetic patient care. Faculty-student conferences are held on a daily basis.

Emphasis is on clinical management of the unconscious patient. Physiology of oxygenation, acid-base balance, and electrolyte disturbances are discussed in depth. Airway problems, oxygen therapy, and drug therapy in resuscitation are reviewed. The course provides the basic knowledge and skills of emergency resuscitation needed by every future intern or resident.

The physiology, diagnosis, and treatment of respiratory failure are also emphasized. Topics include pre-and post-operative care, long-term respirator treatment, and pain and its treatment.

Additionally, students will have exposure to anesthetic management during cardiac and thoracic surgery, obstetric emergencies, infant resuscitation and pediatric surgery. The effects of anesthetics and other drugs on respiration, circulation, and neuromuscular function are reviewed.

Greenberg

All quarters

Prerequisite: medical student and consent of instructor

Independent study.

Staff

All quarters

Cellular and Molecular Medicine

CMM 220. Cancer Biology Journal Club

Prerequisite: Permission of the instructor

Students present and critically analyze papers from the literature on the biology, cell biology, molecular biology, and biochemistry of cancer.

Dowdy

Fall quarter

CMM 225. Essentials of Glycobiology
(cross-listed with BGGN 236, BIOM 222, CHEM 237, MED 225)

Prerequisite: none

Advanced elective for graduate/medical students who have had core courses in cell biology or biochemistry. Expert faculty will present a coordinated overview of the field of Glycobiology, which explores the structure, synthesis and functions of sugar chains in biological systems.

Esko

Spring quarter

CMM 246. Current Literature in Glycobiology
(cross-listed with MED 246)

Prerequisite: graduate or medical student

Students will hear informal presentations on topics of current interest in glycobiology as represented in the current scientific literature.

Varki

Fall, winter and spring quarters

Family and Preventive Medicine

FPM 221. Cardiopulmonary Risk Factor Assessment

Prerequisite: none

The cardiopulmonary risk factor assessment is a standardized protocol offered for incoming first year medical students. It gives new students an opportunity to learn their own health status. Individualized data are being used as a teaching vehicle to acquaint students with issues of assessment, evaluation, interpretation, and modification of risk factors for cardiovascular and pulmonary diseases.

Ries, Criqui

Fall quarter

Prerequisite: graduate or medical student

A second course in Biostatistics. Emphasis on core methods of data analysis. Topics include regression models, analysis of variance, analysis of co-variance, categorical, survival, and non-parametric methods.

Thomas, Jain

Spring quarter

Prerequisite: medical student

The students will learn about some common stress-related problems faced by physicians and patients, some common approaches to their management, and some basic skills that they can apply to their own lives and the lives of their patients.

Beck, Kallenberg

Winter quarter

Prerequisite: none

This course provides both theoretical and practical information about the field of preventive medicine. Subjects covered include health promotion and behavior change, screening for disease and case finding, risk factor identification, exercise and health, environmental and occupational health, and the practice of preventive medicine within the public health arena.

Staff

Winter quarter

Prerequisite: consent of instructor

This course provides an overview of the epidemiology of cancer in the U.S. as well as an in depth discussion of controversies about the causes of specific cancers. Epidemiologic evidence supporting or refuting those theories, including published articles, will be critically reviewed.

Staff

Winter quarter

Prerequisite: enrollment in SM 208 or consent of instructor

Students who wish to gain experience in the epidemiological analysis of published or original data in one chosen area may do so during this directed reading program. Students meet weekly with one instructor to discuss their project. They must submit a written analysis of data or a referenced project proposal based on an analysis of data at the completion of the elective. Project topics are selected by the students and have included epidemiology of infectious diseases, cancers, cardiovascular diseases and nutrition, among others.

Barrett-Conner

Fall, winter, and spring quarters

Prerequisite: familiarity with fundamental concepts in statistics and probability at an intermediate level.

A first course in the Bayesian approach to Biostatistics. Emphasis is on how to apply Bayesian methods in practice and why this approach offers a more realistic analysis in some medical applications. Topics include regression models, random effects models, survival analysis, measurement error, and Bayes Factors.

Jain

All quarters

Prerequisite: none

This guest-lectured weekly seminar will address the cause (e.g. AIDS, substance abuse), diagnosis, and treatment of various obstetric-pediatric diseases through a medical, legal, and epidemiologic perspective.

Klonoff-Cohen, Moore

Winter quarter

Prerequisite: none

Clinical nutrition is the study of nutrition and diet as related to the prevention and treatment of human disease. Nutrition is an interdisciplinary field of study, built on a foundation of biomedical and behavioral sciences. This course emphasizes class discussion of clinical topics and assigned readings in current areas of research and practice (i.e., diet and cancer, vitamin and other diet supplements), with case studies and illustrative class exercises.

Rock

Fall quarter

Prerequisite: None.

The objective is to introduce first and second year medical students to the foundations of Oriental Medicine, including 5 element theory, 4 pillars, tongue and pulse diagnosis, the principles for external invasions, and very simple differential diagnosis. Adjunct therapies will include acu-moxa therapy, acupressure, cupping, gua-sha, and herbal medicine, with an emphasis on treating western medical conditions. Upon completion of the course, students should be able to reasonably discuss with their patients the possible applications and scope of acupuncture, and assess whether it may be beneficial. A combination of didactic information and case studies will be used to demonstrate the application of Oriental Medicine. Guest lectures by practitioners with specialties in pediatrics, obstetrics, and oncology may be included. An understanding of Oriental Medicine will help medical students to make informed and appropriate referrals to competent alternative practitioners if desired by their patients, and encourage further dialog with their patients as to other modalities that they may be using.

Simon

Fall quarter

Prerequisite: consent of instructor

This weekly seminar will explore leading health concerns for women from a sociological as well as a medical viewpoint. The course will include panel discussions and guest lecturers; for example, volunteers from support groups and crisis centers, patients, and physicians.

Wingard

Winter and spring quarters

Prerequisite: medical student or UCSD seniors with instructor's consent

Lecture Range: ethnobotany, paleopathology, other cultural medical systems, culture in doctor/patient relationships, cultural foundations of Western medical thinking in experimentation, epidemiology, and clinical practice. Legal issues and what happens when diverse cultural medical choices are presented to patients.

Ross

Spring quarter

Prerequisite: medical student

This course provides an introduction to clinical ambulatory medicine for the pre-clerkship student. Students spend one afternoon/week in a family physician's practice participating in patient care to the degree commensurate with the student's training. The student and preceptor may opt to continue the course over successive quarters or enroll full time during the summer for up to 4 weeks.

Searfus

All quarters

FPM 239. Cross-Cultural Health Care in Honduras
(Cross-listed with PEDS 239)

Prerequisites: Completion of first-year of medical school at UCSD SOM

After completion of their first three quarters of medical school, students travel to Tela, Honduras, to broaden their perspectives of health care by studying and participating in health care delivery in a developing country. In the Hospital Tela Integrado, a secondary-care level facility operated by the Ministry of Health, students observe daily rounds and patient care activities in the medical, surgical, ob/gyn, and pediatric wards. In the regional affliliated community health centers, under the direct supervision of the medical staff, students assist in providing ambulatory care, patient education, and other health outreach services. Opportunities are available for independent research.

San Miguel,Daley

Summer

Prerequisite: SOMI 202D or consent of instructor

This course will provide an introduction to the nature and problems of aging with emphasis on socio-economic and health status; determinants of priorities of social and health policies will be examined through analysis of the structure and organization of selected programs for the elderly. Field visits will constitute part of the course.

Brody, Simon

Spring quarter (even-numbered years)

Prerequisite: UCSD SOM student in good standing, minimal working knowledge of Spanish. Not open to third year students.

Integrated clinical and public health experience with U.S. and Mexican graduate student and faculty teams over 4 days in Baja, CA, Mexico; emphasis on common clinical and public health problems in underserved populations.

Simon

All quarters

Prerequisite: medical student

The sociocultural, economic, and geo-political framework for the study and understanding of medical problems on a worldwide scale, and as basis for international health policy is presented. Using global patterns of disease, availability and needs for medical technology, and comparisons between diverse medical education and health care delivery systems abroad with those in the United States, students should be able to acquire an understanding of diverse determinants of disease and of relationships between socioeconomic development and health.

Simon

Winter quarter

Prerequisite: SOMI 208 or consent of instructor or graduate students

An introduction to the history and epidemiology of work-related disease. A review of occupational-related health problems, i.e., heart disease, pneumoconiosis, peripheral neuropathy, sterility, birth defects, psychiatric problems. Emphasis on the occupational history in the diagnosis of job-related disease and disability. Major modalities of prevention and control will be presented and the role of health practitioners, government, management, and labor will be reviewed. The course will include guest lecturers, films, videotapes, and field visits to local industries and/or clinicians treating occupational diseases.

Heifetz, Barrett-Connor

Fall quarter

Prerequisite: none

This seminar is designed to expand the student's understanding of clinical epidemiology by investigating several major controversial issues, such as dietary habits and exercise in the prevention of coronary heart disease, clinical consequences of low-level lead poisoning, and trace elements in the prevention of cancer. The seminar will address clinical and methodological issues in the epidemiology of various chronic diseases.

Criqui

Spring quarter

Prerequisite: none

The student participates in an organized system for the delivery of some type of health service (clinic, hospital, health agency, etc.) at selected intervals, reviews relevant readings, and develops a brief analysis of a defined problem in health care. Projects may involve any aspect of health organization and care delivery, including health manpower, quality assessment, medical and epidemiological factors, costs, legal/ethical issues, politics, etc. Can also be used for literature reviews on health care delivery and health policy questions and in planning independent study projects. Consultation with other faculty can be arranged.

Kaplan

Fall, winter, and spring quarters

Prerequisite: second-year medical student

This course is designed to develop the ability to communicate and relate to Spanish-speaking patients. Special emphasis is given to developing interviewing skills to obtain a complete medical history in Spanish. Clinical experiences in Spanish-speaking communities are featured in order to practice interviewing skills while culturally immersed. This course is open to beginners with little or no background.

NOTE: Since the purpose of the whole course is to acquire oral proficiency, enrollment is required for all three consecutive quarters (full academic year). A certificate of accomplishment will be issued at the conclusion of the course.

Simon

Fall, winter, and spring quarters

Prerequisite: three years of high school Spanish/one year of college Spanish, Family and Preventive Medicine 251 A,B,C or equivalent

This course is designed to develop and enhance the working knowledge of medical Spanish that will enable students to communicate and relate to Spanish-speaking patients. Special emphasis is given to develop interviewing skills to obtain a complete medical history and to perform physical examinations and procedures in Spanish. Clinical experiences in Spanish-speaking communities of San Diego are featured in order to practice interviewing skills while culturally immersed.

NOTE: Since the purpose of the course is to acquire oral proficiency, enrollment is required for all three consecutive quarters unless proficiency is demonstrated earlier. The course is open in the spring quarter for selected intermediate/advanced students who may achieve proficiency in one quarter. Certificate of accomplishment/proficiency will be issued on completion of the course.

Simon

Fall, winter, and spring quarters

Prerequisite: none

Critical seminar of important issues in health policy and/or care organization, and medical decision making. Focus on implications for practicing physicians, as well as national, state, and local decision-making. The specific focus of this seminar may depend on student interest. Topics can include medical decision-making, health care financing, or policy analysis.

Kaplan

Spring quarter

Prerequisite: none

This course will provide an overview of the problem of cancer and its avoidable causes. It covers some of the hottest topics currently facing cancer prevention professionals as they try to prevent cancer from occuring in the first place and delay its progression.

Pierce

Spring quarter

Prerequisite: Graduate students in PhD program in Public Health

This three quarter sequence is a combination of didactic instruction, interactive sessions, student presentations, and presentations of current work by JDP faculty. Issues of study design, data management, and current controversies in epidemiologic research will be addressed through discussions and review of published research.

Wingard

Fall, winter, and spring quarters

Prerequisite: graduate student in Public Health PhD program

Students will explore an epidemiologic research question by reviewing relevant published literature, and then design and conduct appropriate data analysis using a pre-existing dataset.

Wingard

Fall quarter

Prerequisite: graduate student in Public Health PhD program

Students will learn the principles of scientific writing, review examples of the scientific literature, and then complete a manuscript suitable for publication based on their project from FPM 259A.

Wingard

Winter quarter

Prerequisite: graduate student in Public Health PhD program

Students will learn the principles of scientific presentations for the classroom and for scientific meetings (both oral and poster presentations). Students will then prepare and deliver presentations based on their project from FPM 259A.

Wingard

Fall, winter, and spring quarters

Prerequisite: SOMI 202D or consent of instructor

The focus is on health care needs of, and programs for, low income and underserved populations. The purpose of this course is to select identified populations with special needs and analyze the factors influencing the incidence of disease and health problems as well as political and legislative measures related to the provision of care. Financial, social, political, and cultural factors will be examined as they affect access and health status.

Brody

Spring quarter (odd-numbered years)

Prerequisite: consent of instructor

For students wishing to pursue advanced studies in selected international health topics. Seminars with senior investigators to assure progress of individually designed projects.

Simon and staff

Fall, winter, and spring quarters

Prerequisite: none

Anton Chekhov was an extraordinary physician and writer. As craftsman and investigator into the varieties of human destiny he can teach us much about being a good doctor. These seminars will explore a selection of Chekhov's short stories and plays.

Schneiderman

Spring quarter

Prerequisite: none

Over 434,000 smoking-related deaths occur each year in the United States. It is also estimated that over 70 percent of United States smokers see a health professional at least once a year. Given that nicotine is one of the hardest addictions to break, this course will explore smoking cessation methods currently available to physicians and their patients.

Zhu

Fall quarter

Prerequisite: none

This hands-on course is designed to develop introductory knowledge of the Macintosh/SPSS editing system (for development of programs) and the SPSS data management language for students who have never used computers before.

Anderson, Kronick

Fall quarter

Prerequisite: Computer literacy

This hands-on course is designed to develop data management and analysis skills using SPSS-MAC for students who are generally familiar with computers, but who have never used SPSS.

Anderson, Kronick

Spring quarter

Prerequisite: none

This course will provide in-depth presentations of the subtle aspects of epidemiologic concepts (bias, confounding, effect modification, study design, etc.). Each class meeting will consist of a lecture presentation as well as discussion of weekly practice problems.

Hollenbach

Spring quarter

Prerequisite: medical student, graduate student, or consent of instructor

Relevant social and cultural theory is introduced in this course to examine ethnic and cultural diversity in health status and health behavior with relevance to disease etiology.

Palinkas

Winter quarter

Prerequisite: medical student, graduate student, or consent of instructor

Relevant social and cultural theory will be introduced in this course to examine ethnic and cultural diversity in health status and health behavior with relevance to primary care and prevention.

Palinkas

Spring quarter

Prerequisite: medical student

The UCSD Student-Run Free Clinic Project operates in partnership with two community programs for the homeless and an inner-city elementary school. Students participate in didactic sessions learning principles of working with the underserved and are supervised in clinical, health education, and administrative roles at the clinic sites.

Beck, Kallenberg

Fall, winter, spring quarters

Prerequisite: medical student

This course is an interactive seminar series wherein successful members of the local and UCSD medical community provide their unique perspectives and routes to success (including necessary preparation) in non-traditional careers. Strategies to sharpen career decision-making will be presented secondarily. Relevant reading will be required.

Covell

Winter quarter

FPM 285A. Clinical Trials I: Issues and Dilemmas in Clinical Trials
(cross-listed with NEU 285A)

Prerequisite: Medical or graduate student

This course will provide students with a comprehensive introduction to the basic concepts and dilemmas of clinical trials. The course will cover methodology and topics will include research design (Phase I - IV), randomization, blinding, sample-size estimation, stopping rules, endpoints and bias, statistical analyses, subgroup analyses, meta-analyses, and ethics.

Raman, Natarajan

Winter quarter

Prerequisite: Medical or graduate student

This course will be taught as a follow-up to FPM 285A (offered in Winter 2004). The course will emphasize applications and implementations by discussing case-studies of clinical trials. It will reinforce the concepts introduced in FPM 285A in each case-study.

Raman, Natarajan

Spring quarter

Prerequisite: FPM 272

The free clinic project operates at three community-based sites. In this class, students, under faculty supervision, provide clinical services and learn administrative, health education and leadership.

Beck, Kallenberg

Fall, winter, and spring quarters

Prerequisite: none

This course provides an overview of the principles and practice of qualitative methods in biomedical and health services research. Case studies and practical experiences will focus on ethnographic fieldwork, extended interviewing, life histories and illness narratives, and focus groups.

Palinkas

Fall and winter quarters

Prerequisite: consent of instructor

Independent study.

Staff

All quarters

Prerequisite: approved ISP proposal

Independent Study Project (ISP).

Staff

All quarters

Prerequisite: Completion of all third year core clerkships or consent of instructor

In this four-week clerkship, the student offers direct primary patient care under the supervision of a member of the Family Medicine academic or community faculty. Student is based at a community clinic, physician's office, HMO, or underserved setting. Student participates in weekly alternative experiences, including home visits to Cambodian refugees, primary care of the homeless, etc., as well as weekly discussion sessions with Dr. Searfus about common problems at different stages of the life cycle.

Searfus

All quarters

Prerequisite: fourth-year medical student

This elective allows fourth-year medical students the opportunity to study in a variety of disciplines. The student selects from a "menu" of experiences to create his or her own clerkship.

Searfus

All quarters

Prerequisite: fourth-year medical student

The Sports Medicine elective is designed to give students a broad range of exposure to the care of the injured athlete. Students will work with sports medicine physicians, physical therapists and trainers and may participate in on-field athletic events. Students will be required to attend weekly didactics, which may include anatomic prosections, radiology conferences, and journal club. The overall intent of this elective is to expose students to a variety of clinical settings focusing on diagnosis, treatment, and prevention of sports-related injuries.

Achar

All quarters

Prerequisite: student must arrange. Must be a fourth-year medical student

Students are supervised in direct primary patient care in a rural setting. Students spend a month working with a rural physician. Depending on students' schedule and location, they participate in didactic sessions and alternative experiences as described in FPM 426.

Searfus

All quarters

Prerequisite: fourth-year medical student; satisfactory completion of FPM 251 or 254 series or equivalent

Students work with native Spanish-speaking clinical preceptors for four-week clerkships in the preceptor's office or clinic. The clerkship is designed to build upon and expand the student's previous education in the Spanish language and in the concepts and problems of cross-cultural communications in clinical settings.

Simon

All quarters

Prerequisites: Completion of third-year of medical school at UCSD.

Under the supervision of physicians at the Hospital Tela Integrado and affiliated community health centers, students have the opportunity to use and improve upon their clinical skills while learning about and participating in health care delivery in a developing country. In the hospital, a secondary-care level facility operated by the Ministry of Health, students participate in daily rounds and patient care activities in the medical, surgical, ob/gyn and pediatric wards. In the community health centers in the Tail region, students assist the medical staff in providing ambulatory care, patient education and health outreach services. Students tailor their activities to specific interests.

Daley

Summer quarter

Prerequisite: Must have completed third year of medical school.

Students will be responsible for primary care of hospitalized family medicine patients under resident and faculty supervision. They will function as interns and will take night call. They will follow patients on the medicine wards as well as on the labor and delivery and postpartum ward. Didactic sessions, (grand rounds, etc.) are every week.

Searfus

Fall quarters

Prerequisite: medical student status and consent of instructor

Independent study.

Staff

All quarters

Prerequisite: none

The assistantship is an eight-week summer program in which students may choose one of the following three options; 1) clinical work with subsequent evaluation of an area of importance in primary care; 2) field work involving problems of health care delivery; and 3) a literature review and subsequent analysis of a clinical subject. Moreover, students have the opportunity to learn more about clinical research methods. Not for credit.

Ganiats and staff

Summer quarter

Medicine

MED 222. Pulmonary Rehabilitation

Prerequisite: medical student

This course introduces the preclinical student to the rationale and clinical practice of pulmonary rehabilitation for patients with disabling lung disease. Students receive classroom instruction and participate actively in the multidisciplinary program which includes patient education, group therapy, and exercise training.

Ries

Fall, winter, and spring quarters

Prerequisite: consent of instructor

Lectures on the molecular and cellular mechanisms of pathogenesis. Topics will include Alzheimer's disease, cell surface and unclear receptors in disease, signal transduction by oncogenes in cancer cells, AIDS, human diseases affecting glycosylation pathways, rheumatoid arthritis, and arteriosclerosis.

Dewji

Spring quarter

Prerequisite: none

Advanced elective for graduate/medical students who have had core courses in cell biology or biochemistry. Expert faculty will present a coordinated overview of the field of Glycobiology, which explores the structure, synthesis, and functions of sugar chains in biological systems.

Esko

Spring quarter

Prerequisite: second-year student or first-year student in the spring quarter

This course will provide the student with an overview of Internal Medicine in clinical and academic community-based settings catering to the medically underserved. We see a wealth of pathology in our resident continuity clinics and students will get a chance to use their Spanish. (Spanish is not a prerequisite)

Moore

Fall, winter, and spring quarters

Prerequisite: second-year student or first-year student in the spring quarter

Students will receive didactic clinical training in the comprehensive management of patients with HIV infection. By participating in multidisciplinary teams, the students will gain knowledge of the ambulatory care of patients with chronic, progressive disease.

Mathews

Fall, winter, and spring quarters

Prerequisite: SOMI 206 or concurrent enrollment in SOMI 206

The behavior of the cardiopulmonary system under various types of stress will be discussed. Specific lectures will be given on diving, high altitude, space, atmospheric pollution, exercise, sleep, and mechanically ventilated patients. The latest research in each topic will be presented during the lectures.

Prisk

Winter quarter

Prerequisite: TB test, LiveScan background check

Monarch School is a high school specifically for homeless teens. Participants in elective Med 229 will participate in team teaching a major portion of their Life Sciences curriculum to these students using a combination of lecture, practical, and one-on-one techniques.

Tighe

Fall and winter quarters

Prerequisite: Admission to UCSD graduate program, School of Medicine, or School of Pharmacy

The Pharmacogenetics course is designed to introduce graduate students, medical students, and pharmacy students to this emerging area of interest, indicating how hereditary mechanisms influence drug responses in humans. The lectures, examples, discussions, and journal presentations will provide the students with a working knowledge of the domains of pharmacology, how heredity influences any response traits, and the ways that advances in genome technologies support our emerging understanding of how polymorphic genetic variants determine inter-individual differences in drug responses. The course will include lectures, discussions, and journal article presentations by students.

O'Connor

Spring quarter

Prerequisite: Medical student

A discovery process for preclinical students to recognize, value, enhance, and preserve human dimension of medicine: the Hippocratic Oath - compassion, service, harmlessness, reverence, covenant - as a way of life. Enables faculty and students to experience non-judgmental, non-competitive, collegial relationships.

Mazuryk, Day, Maly

Winter quarter

Prerequisite: Standard undergraduate biology courses

The course is designed to introduce or re-introduce histology and histopathology of the various organ systems to those who need to analyze mouse tissues as an essential part of their research.

Varki

Fall quarter

Prerequisite: First or second year medical students or permission of instructor

We will review the sociological phenomena of alternative medicine, as well as the history and explanatory models of its most important examples. We will explore the potential interactions of alternative medicine with mainstream scientific medicine

Bressler

Winter quarter

Prerequisite: SOMI 204

This multidisciplinary course integrates the studies of the pathogenesis of atherosclerosis, with emphasis on lipoprotein metabolism, and the cellular and biochemical mechanisms of lesion development. Topics will include the relationship of coronary heart disease to genetic hyperlipoproteinemia, the management of risk factors, and possible therapeutic approaches to atherosclerosis. Two-hour lectures.

Palinski

Spring quarter

Prerequisite: BE 231A or equivalent

This course will give an overview of heart and vascular development and disease from a molecular biological perspective. Current approaches for generating mouse models of cardiovascular disease and recently develped technologies for physiological assessment in small animal models will be presented.

Evans, Chen

Spring quarter

Prerequisite: Concurrent enrollment in SOM 206-206L, or consent of instructor

This course will provide an opportunity for students to further their understanding of selected topics in physiology and pharmacology. Each session will consist of an informal presentation by the instructor followed by discussion. Study questions will be distributed.

Laiken

Winter quarter

Prerequisite: none

Course will cover aspects of the development of ideas in physiology and pharmacology and will be taught in parallel with Organ Physiology (SOMI 206-206L) and Principles of Pharmacology (SOMI 217).

West

Winter quarter

Prerequisite: graduate or medical student

Students will hear informal presentations on topics of current interest in glycobiology as represented in the current scientific literature.

Varki

Fall, winter, and spring quarters

Prerequisite: medical student

This course provides an introduction to clinical geriatric medicine for the pre-clerkship student. Students spend one afternoon each week in a geriatrician's practice participating in patient care to the degree commensurate with the student's training. Emphasis will be on how the elderly patient differs from the younger adult in presentation of illness, work-up, and management.

Ramsdell and staff

Fall, winter, and spring quarters

Prerequisite: none

This pre-clinical, lecture-based course will focus on major health issues associated with the aging patient. Students will have the opportunity to develop and enhance their clinical knowledge base of geriatric medicine-diagnosis and treatment.

Parker, Schneider

Winter quarter

Prerequisite: graduate or medical student

This course emphasizes modern approaches and methodologies for investigating physiological processes in normal and pathological conditions. This includes the application of transgenic, knockout, adenovirus gene therapy, antisense, and cellular imaging technologies in animal models.

Hogan

Spring quarter

Prerequisite: SM 206

While the ability to interpret ECGs is traditionally acquired in the clinical years, many aspects can be learned prior to commencing clinical training. This course presents the fundamentals of ECG interpretation and a systematic approach to reading ECGs.

Laiken

Spring quarter

Prerequisite: consent of instructor

Modern techniques of laboratory investigation will be presented in depth with the goal of facilitating students' laboratory skills. Topics will be drawn from the fields of protein and polysaccharide biochemistry, cell physiology, molecular biology, immunology, and environmental health.

Webster, Arden

Fall quarter

Prerequisite: core courses in biomedical science Ph.D. program, or permission of instructor

This course will cover most of today's key aspects in the organization and dynamics of the immune system and it's regulation. It will provide students with a basis for understanding the physiology and the functioning of the immune system in normal and pathological states.

Zanetti

Winter quarter

Prerequisite: medical student

This introductory course is designed to develop a working knowledge of medical Mandarin that will enable the student to communicate with Mandarin-speaking patients. There will be instruction in basic medical vocabulary and grammar, with a focus on taking a medical history. This is only a conversational course, and no previous knowledge of Mandarin is required.

Hu

Spring quarter

Prerequisite: none

This course covers aspects of physiology related to exercise medicine and health. Areas such as responses to exercise, nutrition and exercise, exercise therapy, and exercise-related injuries will be developed. Course is especially pertinent to students with an interest in sports medicine and healthy lifestyle promotions.

Richardson and staff

Spring quarter

Prerequisite: medical student or consent of instructor

Using lectures and discussion groups, the basic science and concepts of different gene delivery systems are introduced. Their applications to animal models relevant to human diseases will also be discussed. Outline strategies and results of mongoing human trials will be developed. Using lectures and discussion groups, students will become familiar with these topics, enabling the student to understand the various concepts and terms involved in this topic and to accomplish independent reading in this field, or related subjects, in the future.

Raz, Tighe

Spring quarter

Prerequisite: second-year medical student

Faculty preceptor and two to four students will examine four volunteer patients with known physical exam findings over a three-hour period each week for eight weeks. After faculty demonstration, students examine the patients under faculty observance. Each week, a different organ system is targeted.

Wagner

Winter quarter

Prerequisite: second-year medical student

Second year medical students are exposed to pathophysiology through their courses. In addition, they obtain physical examination skills through the Introduction to Clinical Medicine course. This elective is designed to teach the medical students to make a connection between symptoms of human disease and their physical findings on examination. The scientific knowledge acquired in the human disease course will be strengthened by lectures and demonstrations about symptoms and physical findings of each disease. Also, physical exam skills will be strengthened by close faculty supervision.

Savoia

Spring quarter

Prerequisite: consent of instructor

Independent study.

Staff

All quarters

Prerequisite: approved ISP proposal

Staff

All quarters

Prerequisite: fourth-year medical student

Students will be exposed to patients having acute cardiac problems leading to placement in the coronary care unit. One student will be assigned monthly to the unit at UCSD Medical Center and will function as a full member of the medical team.

Ben-Yehuda

All quarters

Prerequisite: fourth-year medical student

A direct patient care experience emphasizing ambulatory care of patients with AIDS and related disorders in the multidisciplinary, primary care model of the UCSD Owens Clinic. Students will also perform inpatient consultations and home visits under faculty supervision.

Mathews

All quarters

Prerequisite: fourth-year medical student

Students will be in dermatology outpatient clinics and conferences twenty-eight hours per week at the UCSD Medical Center and the Veterans Affairs Medical Center (VAMC). In addition to performing biopsies, fungal mounts, and other diagnostic procedures, students will evaluate one to three new patients per clinic, emphasizing dermatologic description and differential diagnosis. This direct patient care experience will enhance a student's ability to properly diagnose, treat, and refer outpatient dermatologic disease.

Goltz

All quarters

Prerequisite: fourth-year medical student

The fourth-year medical students will see patients with a variety of medical and surgical problems during this clerkship in the triage and emergency room areas of the VAMC. All cases will be discussed with experienced attendings and residents.

Sedaghat

All quarters

Prerequisite: fourth-year medical student

This clerkship encompasses training in the examination of the cardiac patient by clinical, electrocardiographic, roentgenologic, and graphic methods. Students participate in patient workup, daily rounds, and weekly cardiovascular conferences.

DeMaria, Lew

All quarters

Prerequisite: fourth-year medical student

Students will be assigned to either the UCSD or Veterans Affairs Medical Center. Under the supervision of a medical resident, students will do one or two new infectious disease consultations a day and present the patients to an attending consultant. Students will follow all their patients until discharge or resolution of their infections. Selected cases will be presented at a weekly conference and at daily microbiology laboratory rounds. The emphases of the elective are the development of clinical skills, and the intelligent use and interpretation of microbiology laboratory results.

Fierer

All quarters

Prerequisite: fourth-year medical student

Students participate in the activities of the Hematology/Oncology Consulting Service. Duties include primarily consultation and management of patients with all forms of malignant tumors, and malignant and non-malignant disorders of the hematopoietic system. The student will also gain experience in the microscopic examination of blood and bone marrow.

Muchmore

All quarters

Prerequisite: fourth-year medical student

In conjunction with residents and fellows on the service, students obtain case histories and perform physical examinations on inpatients referred to the endocrine and metabolic services; then present the cases to the attending physicians. Diagnosis and management of endocrine and metabolic diseases are emphasized with special attention to pathophysiology. Students participate in the endocrine and metabolic outpatient clinics and the weekly combined conference.

Edelman and staff

All quarters

Prerequisite: fourth-year medical student

Under direct supervision of faculty from General Internal Medicine and Psychiatry, fourth-year medical students learn to diagnosis and treat medical and psychiatric aspects of alcohol and drug dependency.

Baxi, Schuckit and staff

Prerequisite: fourth-year medical student

Students are active members of the clinical service of the pulmonary division. They participate in the full range of consultation services and conferences of the division.

Morris, Bigby, and staff

All quarters

Prerequisite: fourth-year medical student

The prevention, diagnosis, and treatment of tuberculosis are important elements of primary care. This elective will include: working with the TB control and skin testing office at UCSD Medical Center, with the TB Clinic at San Diego County Health Department, and with the TB Adult Clinic as well as the Pediatric TB Clinic at UCSD Medical Center; observing medical technologists in the TB microbiology lab; home visits with County of San Diego Public Health Nurses; and community visits with Field Epidemiologists reviewing contact evaluations.

Catanzaro

All quarters

Prerequisite: Must be a fourth-year medical student

The student will work with a palliative medicine consultation team in the acute care setting. The team will consist of a nurse practitioner, hospice fellow, and an attending physician. The student will also participate in didactic conferences held weekly at San Diego Hospice, and see patients in clinic one afternoon a week at San Diego Cancer Center.

Cederquist

Fall, winter, and spring quarters

Prerequisite: fourth-year medical student

Students participate in the activities of the clinical pulmonary physiology laboratory encompassing physiologic assessment of patients with cardiorespiratory disease. Basic physiologic principles, pathophysiologic alterations, and interpretation are stressed.

Morris

All quarters

Prerequisite: fourth-year medical student

On this General Medicine Consult Service, students learn to perform medical evaluations of patients on non-medical services. The art of consultation and the importance of effective communication between colleagues to optimize patient care will be emphasized. The preoperative medical evaluation, surgical risk factors, peri-operative preventative measures, and treatment of postoperative complications will be addressed.

Maynard

All quarters

Prerequisite: fourth-year medical student

The student is a subintern in the intensive care units of the Veterans Affairs Medical Center, rotating responsibility for primary patient care with the housestaff under the supervision of the attending cardiologist and internist.

Maisel

All quarters

Prerequisite: fourth-year medical student

This course is a four week introduction to the multidisciplinary medical/functional evaluation and management of the elderly, with emphasis on the demented patient. Both clinical and didactic instruction methods will be used, with some direct patient care experience.

Ramsdell

All quarters

Prerequisite: fourth-year medical student

Students will participate in consultation rounds, renal clinic, renal transplant clinic, weekly renal conferences and a bimonthly Journal Club meeting. Familiarization with the value of urine sediments exams will be emphasized utilizing an extensive file of preserved urine sediments and fresh material from new consultations. Current basic concepts of dialysis and transplantation will be obtained from in- and out-patients programs during the students' rotations.

Mullaney

All quarters

Prerequisite: fourth-year medical student

This clerkship will expose students to issues related to stem cell transplantation, such as: donor identification, HLA typing, the patient screening process, recruitment, storage and infusion of stem cells, conditioning regimes, clinical indication for autologous and allogeneic transplantation, short and long term side effects, GVHD and post-transplant supportive care. This clerkship will allow the student to understand the complexity of the transplant process and patient care during this procedure.

Carrier

All quarters

Prerequisite: Medicine 401

Students will serve as externs on the Gastroenterology Services at the University Hospital and V.A. Hospital and be an active member of the Division. Students will thoroughly evaluate patients with G.I. Diseases. They will be expected to become thoroughly introduced to the G.I. physiology, clinical aspects, and pharmocology.

Carethers, Garvie

All quarters

Prerequisite: fourth-year medical student

Students become active members of the inpatient consultative services and outpatient arthritis clinics at Veterans Affairs Medical Center and UCSD Medical Center. They are taught to diagnose the common rheumatic diseases by learning how to do an accurate physical examination of the joints, to interpret laboratory studies, and to formulate an intelligent differential diagnosis. The student will work-up and present cases to the fellow and attending, and follow the course of patients during the rotation.

Kavanaugh

All quarters

Prerequisite: fourth-year medical student

Students will work in a medical intensive care unit as the primary physician for a limited number of patients. Emphasis is placed on pathophysiology of acute organ failure. The clerkship provides opportunity to become familiar with the management of critically ill patients.

Fedullo

All quarters

Prerequisite: fourth-year medical student

Student to act as primary physician for ambulatory patients with medical disorders. Students will be responsible for initial and follow-up patient visits under supervision of senior residents and faculty. Student will be assigned to VA Outpatient Clinic/Mission Valley.

Bell, Thorisdottir

All quarters

Prerequisite: fourth-year medical student

Advanced medicine inpatient clerkship at the Indian Health Service Hospital at Tuba City, Arizona. Student will work closely with a medical resident and clinical faculty of a small inpatient service at the hospital. The hospital is located east of the Grand Canyon in the Navajo-Hopi area.

Selzer

All quarters

Prerequisite: fourth-year medical student

This course offers one month of direct patient care experience on the wards of either the Veterans Affairs Medical Center or UCSD Medical Center. The student will assume the duties of a medicine intern under the careful supervision of the resident and attending, evaluating, and providing care for every third patient admitted to the ward. Course director will assign student to location.

Schoene

All quarters

Prerequisite: fourth-year medical student

Students assume many of the responsibilities of interns in settings in which they will be supervised by medical residents and departmental faculty. Students will be assigned to Mercy Hospital.

Heffernan

All quarters

Prerequisite: medical student and consent of instructor

Independent clinical study for medical students.

Staff

All quarters

Neurosciences

NEU 222. Molecular & Cellular Neuroendocrinology

Prerequisite: none

This course will examine the role of the CNS in controlling reproductive functions, stress, growth, and behavior, with emphasis on the cellular and molecular mechanisms of neuroendocrine function. The lectures will be given by experts on each of the subjects. Lectures will include a basic introduction on the topic followed by a description of the current research in the area.

Vale

Fall quarter (even-numbered years)

Prerequisite: none

This class will give a thorough introduction to meditative practice and its relation to the healing interaction. We will practice a simple form of meditation focused on the breath. The class will feature guest speakers who are teachers of meditation and a review of the research investigating the psychological, physiological, and medical effects of meditation.

Geyer

Winter quarter

Prerequisite: medical student or consent of instructor

This lecture and seminar course surveys the neuroanatomy and neurophysiology of the central and peripheral taste and olfactory systems. Plasticity of the mature and developing chemosensory systems will also be covered. Behavioral studies of sensory function will be related to psychophysical studies in humans, including those directed at evaluating clinical chemosensory disorders. Students are expected to discuss readings of journal articles.

Whitehead

Spring quarter

Prerequisite: none

This course will cover "ethical" issues in academia, including dishonesty, plagiarism, attribution, sexual misconduct, etc. We will also discuss "survival" issues, including job hunting, grant preparation, journal reviews, writing letters of recommendation, mentoring, etc.

Kalichman, Elman

Fall quarter

Prerequisite: Neurosciences 238 or Psychology 231 and consent of instructor

Psychological processes including attention, perception, and memory will be studied in connection with event-related potentials of the human brain. The interrelations among psychological and physiological events will be explored in order to arrive at unified concepts of human information processing.

Hillyard

Fall quarter (even-numbered years)

Prerequisite: consent of instructor

Students will learn forms of scientific communication. This includes practical exercise in scientific writing and short oral communication and in criticism and editing. Also covered are preparation of illustrations; preparation of proposals; scientific societies and the history of scientific communication. Emphasis on examples from neurosciences.

Kalichman

Spring quarter

Prerequisite: none

Neuroanatomy course taught in conjunction with Mammalian Neuroanatomy (256). Laboratories deal with gross and microscopic Neuroanatomy of brain systems. Sessions include microscopic analysis of histological sections and observations and dissections of human brain material.

Northcutt

Winter quarter

Prerequisite: medical or graduate student in neurosciences or consent of instructor

The purpose of this course is to introduce graduate students in the neurosciences to research methods used in electron microscopy (EM), through one hour of formal lecture, one hour of seminar, three hours of demonstration, and three hours of supervised laboratory work per week. Students will become familiar with thin sectioning EM, scanning EM, and freeze-fracture EM.

Ellisman

Spring quarter (odd-numbered years)

Prerequisite: medical or graduate student or consent of instructor

Cellular and development aspects of the nervous system. Methods of investigation and culture approaches. Basic neuroembryology and selected examples of regional developments. Neuroglial cells and neuron-glia interactions. Extrinsic controls of survival growth and maturation of neural cells. Neurite growth and synapse formation. Potential for plasticity and regeneration in the nervous system.

Ranscht, O'Leary

Spring quarter (odd-numbered years)

Prerequisite: neurochemistry, neuroanatomy, biochemistry

Molecular and cellular approaches to the study of the nervous system are advancing neurobiology at an increasingly rapid pace. This graduate level course will address the latest molecular advances in the areas of: 1) synapse formation, neurotransmitter release, and neurotransmitter receptors; 2) nerve growth factors, their receptors, and neuronal apoptosis; 3) transcriptional regulation in the brain and peripheral nervous system; 4) cell culture, transgenic, and knock-out mouse model systems; 5) the molecular bases of genetic, psychiatric, and degenerative diseases of the nervous system; and 6) the current molecular knowledge of vision, sensory transduction, circadian rhythms, learning, memory, and behavior.

Mellon

Fall quarter

Prerequisite: Neurosciences 238, SOMI 205, Neurology resident, or consent of instructor

Using the Journal of Electroence-phalography and Clinical Neurophysiology as a core text, subjects chosen from the journal will be discussed and critically evaluated by the participants, and the literature pertinent to each topic reviewed. Illustrative clinical cases will be presented.

Iragui

All quarters

Prerequisite: consent of instructor

Neurosciences group faculty members and graduate students will present and discuss ongoing research. Attendance will be mandatory for first- and second-year graduate students. Faculty, advanced graduate students, medical students, postdoctoral trainees, and other interested parties are encouraged to attend.

Isaacson

Fall, winter, and spring quarters

Prerequisite: graduate students

An examination of the molecular and biochemical bases of drug and transmitter action. The course is devoted to receptor mechanisms, neuropharmacology and drug action on excitable tissues.

Geyer

Spring quarter

Prerequisite: Medical or graduate student

This course will provide students with a comprehensive introduction to the basic concepts and dilemmas of clinical trials. The course will cover methodology and topics will include research design (Phase I-IV), randomization, blinding, sample size estimation, stopping rules, endpoints and bias, statistical analyses, subgroup analyses, meta-analyses, and ethics.

Raman, Natarajan

Winter quarter

Prerequisite: Medical or graduate student

This course will be taught as a follow up to FPM 285A (offered in Winter 2004). The course will emphasize applications and implementations by discussing case-studies of clinical trials. It will reinforce the concepts introduced in FPM 285A in each case-study.

Raman, Natarajan

Spring quarter

Prerequisite: consent of instructor

Independent study.

Staff

All quarters

Prerequisite: approved ISP proposal

Independent Study Project (ISP).

Staff

All quarters

Prerequisite: consent of instructor

Independent study.

Staff

All quarters

Prerequisite: fourth-year medical student

Subinterns are responsible for the primary care of hospitalized pediatric neurology patients and outpatients under direct resident and attending physician supervision. They will perform procedures such as lumbar puncture and participate in night call, daily teaching rounds, neurology grand rounds, and Journal Club.

Trauner

All quarters

Prerequisite: fourth-year medical student

The student will rotate through the general and subspecialty (stroke, epilepsy, headache, nerve, and muscle) neurology clinics based at UCSD Medical Center. Lectures and clinical conferences will be attended as well.

Jackson

All quarters

Prerequisite: fourth-year medical student

Students will participate in the medical, functional, and rehabilitation workup of spinal cord injury patients, with emphasis on the interdisciplinary team approach. Identification of rehabilitation problems and goals, as well as common medical complications, will be stressed.

Gerhart

All quarters

Prerequisite: medical student status and consent of instructor

Independent study.

Staff

All quarters

Opthalmology

OPTH 296. Opthalmology Independent Study

Prerequisite: consent of instructor

Independent study.

Staff

All quarters

Prerequisite: approved ISP proposal

Independent Study Project (ISP).

Staff

All quarters

Prerequisite: fourth-year medical student

This one-month rotation exposes the student to subspecialty training in cornea and external ocular diseases, refractive surgery, retinal diseases, glaucoma, pediatric opthalmology, neuropthalmology, and pathology. In addition, the student participates in all conferences and may participate in surgery.

Granet

All quarters

Prerequisite: medical student and consent of instructor

Independent study.

Staff

All quarters

Orthopedics

ORTHO 220. Introduction to Orthopedics

Principles of Orthopedics to first and second year medical students, including the diagnosis and treatment of low back pain, foot and ankle sprains, common sports injuries, basic orthopedic emergencies, and will introduce casting and splinting techniques.

Meyer

Winter

Prerequisite: consent of instructor

Independent Study

Staff

All quarters

Prerequisite: approved ISP proposal

Independent Study Project (ISP)

Staff

All quarters

Prerequisite: fourth-year medical student

Training is provided in diagnosis and treatment of acute and chronic diseases of the musculoskeletal system while participating in the capacity of an intern on a busy service. Exposure to treatment of trauma, reconstructive surgery and rehabilitation, hand and upper extremity, knee, and general orthopedics. Participation in surgery, rounds, clinical, and may attend weekly CME conferences. Students have direct clinical responsibility, including night call.

Meyer

All quarters

Prerequisite: fourth-year medical student

Training is provided in office orthopedics during daily outpatient clinics in orthopedics and rehabilitation. Students participate in preop consultations, follow-up of postop patients, and numerous ER referrals. In addition to general orthopedics, clinics include pediatric orthopedics, prosthetics and diabetic foot, spine, rehabilitation, hand and upper extremity, knee, and nonhealed fractures. Further ER exposure is available if desired.

Schwartz

All quarters

Prerequisite: fourth-year medical student

Students will participate as a subintern on a busy orthopedic service dealing with acute and chronic problems. Students will be offered unique opportunities for hands-on care in the emergency room, on the wards, the operating room, and in the general and specialty clinics (i.e., spine, hip , knee, sports , shoulder, foot/ankle), which are held weekly. Students will have direct clinical responsibility. Participation in teaching rounds, conferences, and seminars is encouraged.

Kim

All quarters

Prerequisite: fourth-year medical student

The primary operative experience in this subinternship in adult reconstructive surgery is total joint replacement. Students attend clinics, surgery, ward rounds, and assume the role of the primary physician with assistance of a second year orthopedics resident.

Bugbee

All quarters

Prerequisite: fourth-year medical student

Training is provided in the diagnosis and treatment of acute and chronic diseases of the spine, while participating in the capacity of an intern on a busy, expanding orthopedic spine service. Students are exposed to the treatment of spinal disorders related to trauma, reconstructive surgery, tumors, deformities, and rehabilitation, as well as some general adult orthopedics. This is primarily inpatient service, with additional outpatient surgical clinical & teaching rounds. Students are encouraged to attend weekly continuing education conferences. Students take in-house calls for ortho trauma service.

Garfin

All quarters

Prerequisite: fourth-year medical student

Students participate as active members of a pediatric orthopedic team (staff, residents, fellow) at Children's Hospital. They have the opportunity to evaluate patients in clinic, read X-rays, assist on surgical cases, and attend excellent teaching conferences. Conditions seen include common fractures, sports injuries, scoliosis, limb length inequality, club foot, and hip disorders.

Wenger

All quarters

Prerequisite: medical student and consent of instructor

Independent study.

Staff

All quarters

Pathology

PATH 221. Molecular Pathology of Cancer

Prerequisite: SOMI 204

The purpose of this course is to present exciting new developments in molecular carcinogenesis with particular emphasis on oncogene expression and functions of oncogenic proteins. The relevance of molecular mechanisms for understanding human cancer will be discussed.

Walter

Spring quarter

Prerequisite: graduate students or consent of instructor

Topics covered in this course include molecular and cellular mechanisms of viral, bacterial and protozoan pathogenesis. Host response and microbial mechanisms of evasion of host defense will also be discussed. Sessions will consist of faculty and student presentations of current literature.

Corbeil

Spring quarter

Prerequisite: graduate standing or consent of instructor

This course provides an overview of the use of mouse models in biomedical research. Sessions will cover general mouse biology, genetics, technologies for generating mutant mice, and focus on model selection, methodological approaches, data interpretation, experimental design and ethics of animal research. Student pa